Home page

ARCHIVIO
Anno
Volume
Fascicolo

Volume 168 - Anno 2017 - Numero 4

Medication-related osteonecrosis of the jaws (MRONJ) and quality of life evaluation: a pilot study

OPEN ACCESS


doi: 10.7417/T.2017.2015

di M. Capocci, U. Romeo, F. Guerra, A. Mannocci, G. Tenore, S. Annibali, L. Ottolenghi

scarica l'OPEN ACCESS

Abstract 

Background
MRONJ (medication related osteonecrosis of the jaws) is a well-known side effect of certain drugs, which are used to influence bone metabolism for the cure of osteo-metabolic or cancer diseases. The aim of this study is to assess the quality of life (QOL) under a physical and mental point of view in patients affected by MRONJ compared with the general population.
 
Methods
The study has been accomplished through the administration of the SF-12 questionnaire: 30 patients of the MRONJ group were evaluated.
 
Results
Significant differences based on the level of education and age of the subjects, on the location and finally on the stage of necrosis of the jaw have been identified. In this pilot study the test sample shows how MRONJ can aggravate the conditions of patients, above all under a physical point of view
 
Conclusions
Prevention of MRONJ and its symptoms as dysphagia, oral pain, immunological compromission and the need of frequent antibiotic therapies is a crucial part of modern oral pathology and dentistry, above all for oncologic patients who already have a general decrease of physical and mental activities, leading to a poor quality of life


Visualizza il file PDF

ATTENZIONE: per accedere al servizio di consultazione online dei file pdf occorre essere abbonati alla rivista ed aver abilitato il proprio pin.
Se non siete ancora abbonati potete abbonarvi e ricevere il pin attraverso il nostro online store.
Per l'attivazione del pin ricevuto, contattare ordini@seu-roma.it
.

18

H Index

SCImago Journal & Country Rank


Società Editrice Universo s.r.l.
Via G.B.Morgagni, 1 - 00161 Roma - tel (06) 4402054 / (06) 44231171, (06) 64503500 fax (06) 4402033